ARIH2 Antikörper (AA 41-140)

Produktnummer ABIN1714290

Dieser Anti-ARIH2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ARIH2 in WB, ELISA, IHC (p), ICC, IF (cc), IF (p) und IHC (fro). Geeignet für Human.

Kurzübersicht für ARIH2 Antikörper (AA 41-140) (ABIN1714290)

Target: ARIH2 (protein ariadne-2 homolog (ARIH2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARIH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ARIH2 Antikörper

Bindungsspezifität: AA 41-140

Homologie: Human,Mouse,Rat,Cow,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ARIH2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ARIH2

Target: ARIH2 (protein ariadne-2 homolog (ARIH2))

Andere Bezeichnung: ARIH2

Hintergrund:

Synonyms: all trans retinoic acid inducible RING finger, Ari 2, Ari-2, ARI2, ARI2_HUMAN, Ariadne 2, Ariadne 2 protein homolog, ariadne homolog 2 Drosophila, ariadne homolog 2, ARIH 2, Arih2, E3 ubiquitin protein ligase ARIH2, E3 ubiquitin-protein ligase ARIH2, HT005, protein ariadne 2 homolog, Protein ariadne-2 homolog, Triad 1, TRIAD1, Triad1 protein, UIP48.

Background: TRIAD1, also known as ARIH2 (ariadne homolog 2) or ARI2, is a 493 amino acid protein that contains one IBR-type zinc finger and two RING-type zinc fingers and belongs to the ariadne subfamily of RBR proteins. Localized to the nucleus, TRIAD1 interacts with UBE2L3 and is thought to act as an E3 ubiquitin-protein ligase, functioning to accept ubiquitin from E2 ubiquitin-conjugating enzymes and transfer the acquired ubiquitin residue to target substrates. TRIAD1 is subject to post-translational DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding TRIAD1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

Gen-ID: 10425